Promising New Immunotherapy treatment for Patients with Mesothelioma
Recently, immunotherapy protocols are changing as researchers from Fukushima University in Japan have come together with the National Cancer Institute to create new additions. As a conventional form of cancer treatment, immunotherapy has been regarded as the one stop shop when it comes to cancer treatment. Immunotherapy has even been used to treat mesothelioma, even though it is a rare form of cancer.
Regulatory T-Cells are the Main focus of the Study
Regulatory T-cells are what researchers are focusing on, these cells typically form around mesothelioma tumors. Regulatory T-cells are often referred to in the medical field as Tregs. If you or a loved one has been diagnosed with stage 4 mesothelioma, this study may be interesting for you. The job of regulatory T-cells is to help the bodies immune system fight diseases. In this regard, the Treg cells can be viewed in a positive light. For mesothelioma patients, however, these cells cause issues when it comes to fighting an autoimmune disease. The cells form barriers that end up protecting mesothelial malignancies against the bodies conventional immune defense mechanisms. A new toxin, referred to as 2E4-PE38, was created by the scientists to attack cells that send request signals to regulatory T cells for malignant tumor protection. So far, the results of the tests have been very successful.
Promising Test Results for 2E4-PE38
Mesothelioma tumors, along with breast and colon cancer tumors, were implanted in mice to be used as test subjects. The new immunotoxin was then injected in the mice that were not in the control group as those mice were left untreated. The reports from this study show that 85% of the treated mesothelioma tumors showed regression. Along with that amazing result, 100% of both breast cancer and colon cancer tumors also showed regression. The most amazing part about this research is that the mice did not develop new tumors after being injected with 2E4-PE38, even after being given more malignant mesothelioma cells.
These results indicate that the immunotoxin not only overpowered the effects of the regulatory T-cells but also a lasting immunity to the cancer cells. In addition, the immunotoxin did not harm the positive effects of T-cells in other tissues throughout the body.
Such a beautiful discovery will certainly make waves for mesothelioma treatment centers nationwide, especially for conventional treatment. However, mesothelioma alternative treatments may be more interesting to you, such as Homeopathy for mesothelioma. For anyone who has been diagnosed with malignant mesothelioma, the asbestos cancer organization is here to help you.